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MERS-CoV Nucleocapsid antibody

MERS-CoV N Reactivity: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7383849
  • Target See all MERS-CoV Nucleocapsid (MERS-CoV N) products
    MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))
    Reactivity
    Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
    Host
    • 1
    • 1
    Rabbit
    Clonality
    • 1
    • 1
    Polyclonal
    Conjugate
    • 2
    This MERS-CoV Nucleocapsid antibody is un-conjugated
    Application
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    Anti-MERS-CoV Nucleocapsid Protein Polyclonal Antibody
    Purification
    Antigen Affinity
    Immunogen
    A synthetic peptide corresponding to the center region of MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein (NP protein)
    Isotype
    IgG
  • Application Notes
    WB 1:1000-1:5000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    0.2 μm filtered solution in PBS
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))
    Alternative Name
    MERS-CoV Nucleocapsid Protein (MERS-CoV N Products)
    Background
    Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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