Myoferlin antibody

Catalog No. ABIN7384124

This Rabbit Polyclonal antibody specifically detects Myoferlin in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Myoferlin antibody (ABIN7384124)

Target: Myoferlin (MYOF)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myoferlin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Myoferlin Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MYOF (NP_038479.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: MYOF

Background: MYOF,FER1L3,myoferlin,Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Molecular Weight:

Observed_MW: 250 kDa

Calculated_MW: 17 kDa/46 kDa/49 kDa/179 kDa/229 kDa/233 kDa/234 kDa

Gene ID: 26509

UniProt: Q9NZM1