SETD2 antibody

Catalog No. ABIN7384153

This anti-SETD2 antibody is a Rabbit Polyclonal antibody detecting SETD2 in IF. Suitable for Human, Mouse and Rat.

Quick Overview for SETD2 antibody (ABIN7384153)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD2 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-SETD2 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SETD2 (NP_054878.5).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Alternative Name: SETD2

Background: SETD2,HBP231,HIF-1,HIP-1,HSPC069,HYPB,KMT3A,LLS,SET2,p231HBP,Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Gene ID: 29072

UniProt: Q9BYW2

Pathways: Tube Formation