WTAP antibody

Catalog No. ABIN7384316

This Rabbit Monoclonal antibody specifically detects WTAP in WB, IP and IHC (p). It exhibits reactivity toward Human.

Quick Overview for WTAP antibody (ABIN7384316)

Target: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This WTAP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R09-9D8

Product Details anti-WTAP Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000 IHC 1:20-1:100 IP 1:20-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WTAP

Target: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Alternative Name: WTAP

Background: DKFZp686F20131,Female-lethal(2)D homolog,FL2D,hFL(2)D,KIAA0105,MGC3925,Mum2,OTTHUMP00000017522,OTTHUMP00000017523,PNAS 132,PNAS-132,PNAS132,Pre mRNA splicing regulator WTAP,Pre-mRNA-splicing regulator WTAP,Putative pre mRNA splicing regulator female lethal 2D homolog,Putative pre mRNA splicing regulator female lethal(2D),Putative pre-mRNA splicing regulator female lethal(2D) homolog,putative pre-mRNA splicing regulator female-lethal(2D),Wilms tumor 1 associated protein,Wilms tumor 1 associating protein,Wilms tumor 1-associating protein,Wilms' tumor 1 associating protein,Wilms' tumour 1-associating protein,WT1 associated protein,WT1-associated protein,WT1-associating protein,wtap,WTAP,also named as KIAA0105 and hFL(2)D,is previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. It is a Pre-mRNA-splicing regulator protein. It is a regulatory subunit of the WMM N6-methyltransferase complex which plays a role in the efficiency of mRNA splicing and processing and mRNA stability. It is required for accumulation of METTL3 and METTL14 to nuclear speckle.

Molecular Weight:

Observed_MW: 55kDa

Calculated_MW: 44kDa

Gene ID: 9589

UniProt: Q15007