Lactate Dehydrogenase A antibody

Catalog No. ABIN7384336

This anti-Lactate Dehydrogenase A antibody is a Rabbit Monoclonal antibody detecting Lactate Dehydrogenase A in WB. Suitable for Human and Rat.

Quick Overview for Lactate Dehydrogenase A antibody (ABIN7384336)

Target: Lactate Dehydrogenase A (LDHA)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Lactate Dehydrogenase A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R09-9A7

Product Details anti-Lactate Dehydrogenase A Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Alternative Name: Lactate Dehydrogenase A

Background: Cell proliferation-inducing gene 19 protein,GSD11,L lactate dehydrogenase A chain,l7R2,LDH M,LDH muscle subunit,LDH1,PIG19 Proliferation-inducing gene 19,LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Molecular Weight:

Observed_MW: 37kDa

Calculated_MW: 37kDa

Gene ID: 3939

UniProt: P00338

Pathways: Warburg Effect