GSDMD antibody

Catalog No. ABIN7384358

This Rabbit Monoclonal antibody specifically detects GSDMD in WB. It exhibits reactivity toward Human.

Quick Overview for GSDMD antibody (ABIN7384358)

Target: GSDMD (Gasdermin D (GSDMD))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GSDMD antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R06-5C5

Product Details anti-GSDMD Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD

Background: DF5L,DFNA5L,FKSG10,GSDMDC1,GSDMD,GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Molecular Weight:

Observed_MW: 53kDa

Calculated_MW: 53kDa

Gene ID: 79792

UniProt: P57764

Pathways: Inflammasome