Interleukin enhancer-binding factor 3 (ILF3) antibody

Catalog No. ABIN7384360

This anti- antibody is a Rabbit Monoclonal antibody detecting in WB, IF and IHC (p). Suitable for Human and Rat.

Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) antibody (ABIN7384360)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R04-3C1

Product Details

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:2000-1:5000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: Interleukin enhancer-binding factor 3 (ILF3)

Alternative Name: ILF3

Background: CBTF,Double stranded RNA binding protein 76,Double-stranded RNA-binding protein 76,DRBF,DRBP76,ILF3,ILF3,Interleukin enhancer binding factor 3,Interleukin enhancer-binding factor 3,M phase phosphoprotein 4,M-phase phosphoprotein 4,MPHOSPH4,MPP4,NF AT 90,NF-AT-90,NF110,NF90,NFAR,Nuclear factor associated with dsRNA,Nuclear factor of activated T cells 90 kDa,Nuclear factor of activated T-cells 90 kDa,TCP80,Translational control protein 80,This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight:

Observed_MW: 95kDa

Calculated_MW: 95kDa

Gene ID: 3609

UniProt: Q12906

Pathways: M Phase