ABCE1 antibody

Catalog No. ABIN7384406

This Rabbit Monoclonal antibody specifically detects ABCE1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ABCE1 antibody (ABIN7384406)

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ABCE1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: R09-8C3

Product Details anti-ABCE1 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABCE1

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Alternative Name: ABCE1

Background: 2' 5' oligoadenylate binding protein,2''-5''-oligoadenylate-binding protein,2'5' oligoadenylate binding protein,ABC 38,ABC38,ABCE 1,ABCE1,ABCE1,ATP binding cassette sub family E (OABP) member 1,ATP binding cassette sub family E member 1,ATP-binding cassette sub-family E member 1,HuHP 68,HuHP68,OABP,Ribonuclease 4 inhibitor,Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L inhibitor,RLI,RNase L inhibitor,RNASEL1,RNASELI,RNS 4I,RNS4I,The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight:

Observed_MW: 67kDa

Calculated_MW: 67kDa

Gene ID: 6059

UniProt: P61221