Angiotensin II Type-1 Receptor antibody
-
- Target See all Angiotensin II Type-1 Receptor (AGTR1) Antibodies
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Monoclonal
-
Conjugate
- This Angiotensin II Type-1 Receptor antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Affinity Purified
- Clone
- R07-1I6
- Isotype
- IgG
- Top Product
- Discover our top product AGTR1 Primary Antibody
-
-
- Application Notes
- WB 1:1000-1:2000
- Restrictions
- For Research Use only
-
- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- Alternative Name
- Angiotensin II Type 1 Receptor (AGTR1 Products)
- Background
- AGTR1,AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R,Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
- Molecular Weight
-
Observed_MW: 41kDa
Calculated_MW: 41kDa
- Gene ID
- 185
- UniProt
- P30556
- Pathways
- JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
-