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Angiotensin II Type-1 Receptor antibody

AGTR1 Reactivity: Human WB Host: Rabbit Monoclonal R07-1I6 unconjugated
Catalog No. ABIN7384413
  • Target See all Angiotensin II Type-1 Receptor (AGTR1) Antibodies
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Reactivity
    • 54
    • 20
    • 18
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 3
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 57
    • 2
    Monoclonal
    Conjugate
    • 32
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiotensin II Type-1 Receptor antibody is un-conjugated
    Application
    • 32
    • 23
    • 17
    • 15
    • 13
    • 9
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Affinity Purified
    Clone
    R07-1I6
    Isotype
    IgG
    Top Product
    Discover our top product AGTR1 Primary Antibody
  • Application Notes
    WB 1:1000-1:2000
    Restrictions
    For Research Use only
  • Concentration
    300 μg/mL
    Buffer
    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Alternative Name
    Angiotensin II Type 1 Receptor (AGTR1 Products)
    Background
    AGTR1,AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R,Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
    Molecular Weight

    Observed_MW: 41kDa

    Calculated_MW: 41kDa

    Gene ID
    185
    UniProt
    P30556
    Pathways
    JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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