BCR antibody (AA 50-100)
Quick Overview for BCR antibody (AA 50-100) (ABIN7448323)
Target
See all BCR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 50-100
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Purpose
- Rabbit anti-BCR IHC Antibody, Affinity Purified
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Predicted Reactivity
- Gorilla
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Purification
- Affinity Purified
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Immunogen
- Between AA 50 and 100
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Isotype
- IgG
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Application Notes
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ICC-IF: 1:50 - 1:500
ICC: 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- BCR (Breakpoint Cluster Region (BCR))
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Alternative Name
- BCR
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Background
- Background: BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.
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Gene ID
- 613
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NCBI Accession
- NP_004318
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UniProt
- P11274
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Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
Target
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