ILK antibody (AA 402-451)

Catalog No. ABIN7448388

The Rabbit Polyclonal anti-ILK antibody (ABIN7448388) specifically detects ILK in IF/ICC. The antibody is reactive with Human samples.

Quick Overview for ILK antibody (AA 402-451) (ABIN7448388)

Target: ILK (Integrin-Linked Kinase (ILK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ILK antibody is un-conjugated

Application: Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-ILK Antibody

Binding Specificity: AA 402-451

Purpose: Rabbit anti-ILK IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Zebrafish,Chicken,Sheep,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,African elephant,Chinese hamster,Spotted green pufferfish,Atlantic salmon,Tasmanian devil,Naked mole rat,Nile tilapia,Little brown bat,Northern white-cheeked gibbon,Three-spined stickleback,Japanese pufferfish,Gray short-tailed opossum,Medaka fish,Thirteen-lined ground squirrel,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 402 and 451

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Alternative Name: ILK

Background: Background: Integrin-linked kinase (ILK) is a serine/threonine kinase associated with the cytoplasmic domain of beta integrins and mediates integrin signaling from the extracellular matrix to the intracellular actin cytoskeleton. PKB/Akt and GSK-3beta are targets of ILK involved in integrin-mediated cell proliferation and cell survival. ILK has been shown to interact with Paxillin, PINCH-1, PINCH-2, and parvin to influence actin dynamics.

Gene ID: 3611

NCBI Accession: NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration