BRD3 antibody (AA 676-726)

Catalog No. ABIN7448441

The Rabbit Polyclonal anti-BRD3 antibody has been validated for IHC. It is suitable to detect BRD3 in samples from Human.

Quick Overview for BRD3 antibody (AA 676-726) (ABIN7448441)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BRD3 Antibody

Binding Specificity: AA 676-726

Purpose: Rabbit anti-BRD3 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Crab-eating macaque,Northern white-cheeked gibbon,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 676 and 726

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3

Background: Background: BRD3 (bromodomain containing 3) is a double bromo-domain containing protein. It has been shown to associate with hyperacetylated chromatin of transcribed genes. From this finding it is suggested that BRD3 plays a role in RNA polymerase II transcription through nucleosomes. A chromosomal translocation resulting in a fusion protein involving BRD3 and NUT has been associated with a rare and lethal carcinoma. [taken from the Universal Protein Resource (UniProt) Q15059 and from NCBI Entrez Gene (Gene ID: 8019)].

Gene ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding