BRD4 antibody (AA 1312-1362)

Catalog No. ABIN7448442

This anti-BRD4 antibody is a Rabbit Polyclonal antibody detecting BRD4 in IHC. Suitable for Human and Mouse.

Quick Overview for BRD4 antibody (AA 1312-1362) (ABIN7448442)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BRD4 Antibody

Binding Specificity: AA 1312-1362

Purpose: Rabbit anti-BRD4 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,West Indian ocean coelacanth,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,African elephant,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 1312 and 1362

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Alternative Name: BRD4

Background: Background: Bromodomain-containing protein 4 (BRD4) contains 2 bromo-domains. Bromo-domains are found in chromatin-associating proteins and can interact specifically with acetylated lysine. BRD4 is described as a chromatin adaptor and has been shown to bind acetylated chromatin. It was originally identified as MCAP (mitotic chromosome associated protein) due to its association with mitotic chromosomes. BRD4 also associates with several transcription complexes such as the Mediator complexes and P-TEFb complexes and is considered to function as a transcriptional co-factor.

Gene ID: 23476

NCBI Accession: NP_490597

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome