CSN2 antibody (AA 1-50)

Catalog No. ABIN7448492

The Rabbit Polyclonal anti-CSN2 antibody has been validated for IHC. It is suitable to detect CSN2 in samples from Human and Mouse.

Quick Overview for CSN2 antibody (AA 1-50) (ABIN7448492)

Target: CSN2 (Casein beta (CSN2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSN2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CSN2 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-CSN2 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Nile tilapia,Crab-eating macaque,Tasmanian devil,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Gray short-tailed opossum,Zebra finch,Naked mole rat,Small-eared galago,Japanese pufferfish,African elephant,West Indian ocean coelacanth,Northern white-cheeked gibbon,Medaka fish,Three-spined stickleback,Spotted green pufferfish,Little brown bat

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CSN2

Target: CSN2 (Casein beta (CSN2))

Alternative Name: CSN2

Background: Background: CSN2 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals a function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN2 has also been demonstrated to interact with the sin3A corepressor complex as well as the thyroid hormone and vitamin D3 receptor to mediate gene repression.

Gene ID: 9318

NCBI Accession: NP_004227

UniProt: P61201