EIF2A antibody (AA 525-575)

Catalog No. ABIN7448543

The Rabbit Polyclonal anti-EIF2A antibody has been validated for IHC. It is suitable to detect EIF2A in samples from Human.

Quick Overview for EIF2A antibody (AA 525-575) (ABIN7448543)

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-EIF2A Antibody

Binding Specificity: AA 525-575

Purpose: Rabbit anti-eIF2A IHC Antibody, Affinity Purified

Predicted Reactivity: Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 525 and 575

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EIF2A

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Alternative Name: eIF2A

Background: Background: Eukaryotic initiation factor 2A (eIF2A) directs binding of the intiator methionyl-tRNA [Met-tRNA(i)] to 40 S ribosomal subunits in a codon dependent manner. It is a 65 kDa protein that was originally believed to be the functional homolog of prokaryotic IF2. eIF2A displays functional qualities similar to eIF2 which exists as complex of 3 subunits (eIF2-alpha, beta, and gamma), however comparison of eIF2A and eIF2 has shown that these two intitiation factors also display distinct functional abilities.

Gene ID: 83939

NCBI Accession: NP_114414

UniProt: Q9BY44

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly