PPP4C antibody (AA 1-50)

Catalog No. ABIN7448739

This anti-PPP4C antibody is a Rabbit Polyclonal antibody detecting PPP4C in IHC. Suitable for Human and Mouse.

Quick Overview for PPP4C antibody (AA 1-50) (ABIN7448739)

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP4C antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PPP4C Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PPP4C IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Small-eared galago,Gray short-tailed opossum,Green anole,Duckbill platypus,African elephant,Chinese hamster,Little brown bat,Thirteen-lined ground squirrel,Naked mole rat,White-tufted-ear marmoset,Northern white-cheeked gibbon,Crab-eating macaque,Tasmanian devil

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPP4C

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Alternative Name: PPP4C

Background: Background: PPP4C, also known as PPX, is the catalytic subunit of the PP4 serine/threonine protein phosphatase. PP4 is a holoenzyme that is comprised of the PPP4C catalytic subunit in association with the PP4-R1 or PP4-R2 regulatory subunits. PP4 has been demonstrated to directly interact with and activate NF-kappaB. PP4 also has been demonstrated to interact with histone deacetylase HDAC3 to influence transcription and to serve a role in microtubule organization during mitosis. Signaling through the MAPK and JNK-1 pathway has also been demonstrated to involve PP4.

Gene ID: 5531

NCBI Accession: NP_002711

UniProt: P60510