SUPT5H antibody (C-Term)

Catalog No. ABIN7448819

The Rabbit Polyclonal anti-SUPT5H antibody has been validated for IHC. It is suitable to detect SUPT5H in samples from Human and Mouse.

Quick Overview for SUPT5H antibody (C-Term) (ABIN7448819)

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPT5H antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SUPT5H Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-SUPT5H IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Ferret,Tasmanian devil,Gray short-tailed opossum,Green anole,Northern white-cheeked gibbon,Naked mole rat,Small-eared galago,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Little brown bat,Chinese hamster

Purification: Affinity Purified

Immunogen: Between AA 1040 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SUPT5H

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Alternative Name: SUPT5H

Background: Background: Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT5H is a subunit of the DRB sensitivity inducing factor (DSIF) along with SUPT4H that functions as a negative elongation factor. DSIF associates with RNA Pol II and may inhibit elongation by pausing and terminating RNA Pol II activity.

Gene ID: 6829

NCBI Accession: NP_003160

UniProt: O00267