Spt6 antibody (AA 425-475)

Catalog No. ABIN7448820

This anti-Spt6 antibody is a Rabbit Polyclonal antibody detecting Spt6 in IHC. Suitable for Human and Mouse.

Quick Overview for Spt6 antibody (AA 425-475) (ABIN7448820)

Target: Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Spt6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Spt6 Antibody

Binding Specificity: AA 425-475

Purpose: Rabbit anti-SUPT6H IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Tasmanian devil,White-tufted-ear marmoset,Crab-eating macaque,West Indian ocean coelacanth,Ferret,Three-spined stickleback,Naked mole rat,Chinese hamster,Spotted green pufferfish,Zebra finch,Japanese pufferfish,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Green anole,Gray short-tailed opossum,Medaka fish,Nile tilapia,African elephant

Purification: Affinity Purified

Immunogen: Between AA 425 and 475

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Spt6

Target: Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))

Alternative Name: SUPT6H

Background: Background: Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT6H is hypothesized to play a role in enhancing the rate of transcription elongation in association with RNA Pol II by mobilizing histones and modulating chromatin structure.

Gene ID: 6830

NCBI Accession: NP_003161

UniProt: Q7KZ85

Pathways: Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response