TBL1XR1 antibody (AA 100-150)

Catalog No. ABIN7448826

The Rabbit Polyclonal anti-TBL1XR1 antibody (ABIN7448826) specifically detects TBL1XR1 in IHC. The antibody is reactive with Human samples.

Quick Overview for TBL1XR1 antibody (AA 100-150) (ABIN7448826)

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1XR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-TBL1XR1 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-TBLR1 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Alternative Name: TBLR1

Background: Background: TBLR1 is a six WD-40 repeat protein with high sequence homology to TBL1 (transducin beta-like protein 1) and is part of the SMRT (silencing mediator of retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor) complexes that interact with nuclear receptors and repress transcription. Biochemical characterization of SMRT and N-CoR complexes demonstrate that SMRT and N-CoR are present in complexes that include HDAC3 (histone deacetylase 3), TBL1, and TBLR1. Association with HDAC3 indicates that these complexes may repress transcription through histone deacetylation and chromatin remodeling.

Gene ID: 79718

NCBI Accession: NP_078941

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha