U2AF1 antibody (AA 140-190)

Catalog No. ABIN7448845

Product Details anti-U2AF1 Antibody

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Binding Specificity: AA 140-190

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This U2AF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-U2AF35 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Guinea pig_10141,Panda,Orangutan,Monkey,Chimpanzee,Purple sea urchin,West Indian ocean coelacanth,Atlantic salmon,Florida lancelet,Duckbill platypus,Tasmanian devil,White-tufted-ear marmoset,Nile tilapia,Crab-eating macaque,Black-legged tick,Soft tick,Gray short-tailed opossum,Thirteen-lined ground squirrel,Japanese pufferfish,Ferret,Small-eared galago,Naked mole rat,African elephant,Medaka fish,Spotted green pufferfish,Water flea,Green anole,Zebra finch,Little brown bat,Three-spined stickleback,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 140 and 190

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for U2AF1

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Alternative Name: U2AF35 (U2AF1 Products)

Background: Background: U2AF35 heterodimerizes with U2AF65 to form the U2 snRNP auxiliary factor which is part of the splicesome. U2AF35 is required for splicing of AG-dependent pre-mRNAs and functions in recognizing the conserved 3' splice site dinucleotide AG. U2AF35 contains an atypical RNA recognition motif (RRM), two C3H1-type zinc fingers, and a C-terminal arginine/serine (RS)-rich domain interrupted by glycines.

Gene ID: 7307

NCBI Accession: NP_006749

UniProt: Q01081