Recombinant CD163 antibody (AA 850-900)

Catalog No. ABIN7448890

This Rabbit Monoclonal antibody specifically detects CD163 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD163 antibody (AA 850-900) (ABIN7448890)

Target: CD163

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BLR087G

Product Details anti-CD163 Antibody

Binding Specificity: AA 850-900

Purpose: Rabbit anti-CD163 Recombinant Monoclonal Antibody [BLR087G]

Immunogen: between AA 850 and 900

Isotype: IgG

Application Details

Application Notes: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: Background: CD163 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. CD163 functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. CD163 may also function as an innate immune sensor for bacteria and inducer of local inflammation. [taken from NCBI Entrez Gene (Gene ID: 9332)].

Gene ID: 9332

NCBI Accession: NP_004235

UniProt: Q86VB7