BRCAA1 antibody (AA 125-175)

Catalog No. ABIN7448931

This anti-BRCAA1 antibody is a Rabbit Polyclonal antibody detecting BRCAA1 in IHC and IF (p). Suitable for Human.

Quick Overview for BRCAA1 antibody (AA 125-175) (ABIN7448931)

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCAA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-BRCAA1 Antibody

Binding Specificity: AA 125-175

Purpose: Rabbit anti-ARID4B IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Green anole,Crab-eating macaque,Tasmanian devil,Thirteen-lined ground squirrel,Zebra finch,Little brown bat,Northern white-cheeked gibbon,Gray short-tailed opossum,Duckbill platypus,Naked mole rat,African elephant

Purification: Affinity Purified

Immunogen: Between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BRCAA1

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Alternative Name: ARID4B

Background: Background: ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.

Gene ID: 51742

NCBI Accession: NP_057458

UniProt: Q4LE39