Filamin A antibody (AA 1725-1775)

Catalog No. ABIN7448965

This Rabbit Polyclonal antibody specifically detects Filamin A in IHC and IF (p). It exhibits reactivity toward Human.

Quick Overview for Filamin A antibody (AA 1725-1775) (ABIN7448965)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Filamin A Antibody

Binding Specificity: AA 1725-1775

Purpose: Rabbit anti-Filamin A IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan,Monkey,Gorilla,Dusky titi monkey,White-tufted-ear marmoset,Olive baboon,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 1725 and 1775

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: Filamin A

Background: Background: Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

Gene ID: 2316

NCBI Accession: NP_001447

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location