HDAC1 antibody (C-Term)

Catalog No. ABIN7448972

The Rabbit Polyclonal anti-HDAC1 antibody has been validated for IHC and IF (p). It is suitable to detect HDAC1 in samples from Human and Mouse.

Quick Overview for HDAC1 antibody (C-Term) (ABIN7448972)

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HDAC1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-HDAC1 IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Ferret,White-tufted-ear marmoset,Small-eared galago,Chinese hamster,Chiru,Northern white-cheeked gibbon,African elephant,Little brown bat,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogen: Between AA 425 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Alternative Name: HDAC1

Background: Background: Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription.

Gene ID: 3065

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis