KIF20B antibody (AA 825-875)

Catalog No. ABIN7449101

The Rabbit Polyclonal anti-KIF20B antibody has been validated for IP. It is suitable to detect KIF20B in samples from Human.

Quick Overview for KIF20B antibody (AA 825-875) (ABIN7449101)

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF20B antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-KIF20B Antibody

Binding Specificity: AA 825-875

Purpose: Rabbit anti-KIF20B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 825 and 875

Isotype: IgG

Application Details

Application Notes: 8 - 15 μL/mg lysate

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KIF20B

Target: KIF20B (Kinesin Family Member 20B (KIF20B))

Alternative Name: KIF20B

Background: Background: Kinesin family member 20B (KIF20B) is a plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). KIF20B is required for proper midbody organization and abscission in polarized cortical stem cells. It plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. KIF20B participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, KIF20B cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. It is involved in cerebral cortex growth (By similarity). KIF20B acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [taken from the Universal Protein Resource (UniProt) Q96Q89].

Gene ID: 9585

UniProt: Q96Q89

Pathways: M Phase