CHD1 antibody (AA 1660-1710)

Catalog No. ABIN7449155

The Rabbit Polyclonal anti-CHD1 antibody has been validated for WB, IP, ChIP and ChIP-seq. It is suitable to detect CHD1 in samples from Human.

Quick Overview for CHD1 antibody (AA 1660-1710) (ABIN7449155)

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-CHD1 Antibody

Binding Specificity: AA 1660-1710

Purpose: Rabbit anti-CHD1 Antibody, Affinity Purified

Predicted Reactivity: Chicken

Purification: Affinity Purified

Immunogen: between AA 1660 and 1710

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

ChIP: 1 - 5 μg

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Alternative Name: CHD1

Background: Background: CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation.

Gene ID: 1105

NCBI Accession: NP_001261

UniProt: O14646

Pathways: Chromatin Binding