FLG2 antibody (AA 100-150)

Catalog No. ABIN7449193

This Rabbit Polyclonal antibody specifically detects FLG2 in WB. It exhibits reactivity toward Human.

Quick Overview for FLG2 antibody (AA 100-150) (ABIN7449193)

Target: FLG2 (Filaggrin Family Member 2 (FLG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FLG2 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-FLG2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 100 and 150

Isotype: IgG

Application Details

Application Notes: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FLG2

Target: FLG2 (Filaggrin Family Member 2 (FLG2))

Alternative Name: FLG2

Background: Background: The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].

Gene ID: 388698

UniProt: Q5D862