SETDB1 antibody (AA 1125-1175)

Catalog No. ABIN7449256

This Rabbit Polyclonal antibody specifically detects SETDB1 in WB. It exhibits reactivity toward Human.

Quick Overview for SETDB1 antibody (AA 1125-1175) (ABIN7449256)

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETDB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SETDB1 Antibody

Binding Specificity: AA 1125-1175

Purpose: Rabbit anti-SETDB1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1125 and 1175

Isotype: IgG

Application Details

Application Notes: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SETDB1

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Alternative Name: SETDB1

Background: Background: SETDB1 (SET domain, bifurcated 1) is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family that functions as a histone and DNA methyltransferase. SETDB1 was identified through its interaction with ERG (ets-related gene) and KAP1 (KRAB-associated protein1) and was later demonstrated to interact with HDAC1/2 (histone deacetylase 1/2), DNA methyltransferase 3s (DNMT3s), mSin3A/3B, HP1, and MBD1. SETDB1 is suggested to play a role in transcriptional repression important to early development.

Gene ID: 9869

NCBI Accession: NP_036564

UniProt: Q15047