SRSF10 antibody (AA 133-183)

Catalog No. ABIN7449386

The Rabbit Polyclonal anti-SRSF10 antibody is suitable to detect SRSF10 in samples from Human. It has been validated for WB and IHC.

Quick Overview for SRSF10 antibody (AA 133-183) (ABIN7449386)

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SRSF10 Antibody

Binding Specificity: AA 133-183

Purpose: Rabbit anti-FUSIP1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine,Pig,Orangutan

Purification: Affinity Purified

Immunogen: between AA 133 and 183

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Alternative Name: FUSIP1

Background: Background: FUSIP1 (FUS-interacting protein 1) was originally identified in a two-hybrid screen for partners of the TLS (translocated in liposarcoma) protein also known as FUS. FUSIP1 is a splicing factor of the serine-arginine (SR) family of proteins. It functions as a splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. FUSIP1 seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70, and it is required for splicing repression in M-phase cells and after heat shock [taken from the Universal Protein Resource (UniProt) O75494].

Gene ID: 10772

NCBI Accession: NP_006616

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization