MTA2 antibody (AA 500-550)

Catalog No. ABIN7449600

This anti-MTA2 antibody is a Rabbit Polyclonal antibody detecting MTA2 in WB and IP. Suitable for Human.

Quick Overview for MTA2 antibody (AA 500-550) (ABIN7449600)

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MTA2 Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-MTA2 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 4 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MTA2

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Alternative Name: MTA2

Background: Background: MTA2 (metastasis-associated protein 2) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA2 is highly similar to MTA1 and was identified as a factor differentially expressed in a carcinoma cell line. MTA2 can repress p53-dependent transcriptional activation by enhancing its deacetylation. MTA1 has also been shown to function as a corepressor for ligand-induced estrogen receptor (ER) transactivation. As part of the NuRD complex MTA2 represses ERalpha transactivation activity by modulating the acetylation status of ERalpha.

Gene ID: 9219

NCBI Accession: NP_004730

UniProt: O94776

Pathways: Chromatin Binding