PAPOLG antibody (AA 686-736)

Catalog No. ABIN7449622

This Rabbit Polyclonal antibody specifically detects PAPOLG in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for PAPOLG antibody (AA 686-736) (ABIN7449622)

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPOLG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PAPOLG Antibody

Binding Specificity: AA 686-736

Purpose: Rabbit anti-PAP-gamma Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 686 and 736

Isotype: IgG

Application Details

Application Notes:

IP: 10 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAPOLG

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Alternative Name: PAP-gamma

Background: Background: Poly(A) polymerase gamma (PAP-gamma) is a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60 % identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. PAP-gamma is exclusively localized in the nucleus and exhibits nonspecific as well as CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity [taken from NCBI Entrez Gene (GeneID: 64895)].

Gene ID: 64895

NCBI Accession: NP_075045

UniProt: Q9BWT3