FOXM1 antibody (AA 713-763)

Catalog No. ABIN7449736

This Rabbit Polyclonal antibody specifically detects FOXM1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for FOXM1 antibody (AA 713-763) (ABIN7449736)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FOXM1 Antibody

Binding Specificity: AA 713-763

Purpose: Rabbit anti-FOXM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 713 and 763

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: FOXM1

Background: Background: FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.

Gene ID: 2305

NCBI Accession: NP_973731

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus