PKD2 antibody (AA 320-400)

Catalog No. ABIN7449790

This Rabbit Polyclonal antibody specifically detects PKD2 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for PKD2 antibody (AA 320-400) (ABIN7449790)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PKD2 Antibody

Binding Specificity: AA 320-400

Purpose: Rabbit anti-PKD2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 320 and 400

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Alternative Name: PKD2

Background: Background: PKD2 is a member of the protein kinase D (PKD) family of serine/threonine protein kinases that belongs to a subfamily of the calcium-calmodulin kinase-like superfamily. PKD2 and its family members are activated by phorbol esters and diacylglycerol generated by PKC activation. PKD2 has been demonstrated to play a role in IL-2 promoter regulation as well as IL-8 production. PKD2 may also be involved in the regulation of trans-golgi network trafficking.

Gene ID: 25865

NCBI Accession: NP_057541

UniProt: Q9BZL6

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity