UMPS antibody (AA 430-480)

Catalog No. ABIN7449854

The Rabbit Polyclonal anti-UMPS antibody has been validated for WB and IP. It is suitable to detect UMPS in samples from Human and Mouse.

Quick Overview for UMPS antibody (AA 430-480) (ABIN7449854)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UMPS antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-UMPS Antibody

Binding Specificity: AA 430-480

Purpose: Rabbit anti-UMPS Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 430 and 480

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Alternative Name: UMPS

Background: Background: UMPS (uridine monophosphate synthase) is a uridine 5'-monophosphate synthase. UMPS is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate [taken from NCBI Entrez Gene (Gene ID: 7372)].

Gene ID: 7372

NCBI Accession: NP_000364

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process