SEC63 antibody (AA 700-750)

Catalog No. ABIN7449917

The Rabbit Polyclonal anti-SEC63 antibody has been validated for WB and IP. It is suitable to detect SEC63 in samples from Human and Mouse.

Quick Overview for SEC63 antibody (AA 700-750) (ABIN7449917)

Target: SEC63 (SEC63 Homolog (SEC63))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC63 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SEC63 Antibody

Binding Specificity: AA 700-750

Purpose: Rabbit anti-SEC63 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SEC63

Target: SEC63 (SEC63 Homolog (SEC63))

Alternative Name: SEC63

Background: Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Translocation protein SEC63 homolog, encoded by the gene SEC63, and the SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway [taken from NCBI Entrez Gene (Gene ID: 11231)].

Gene ID: 11231

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling