ADA antibody (AA 100-150)
Quick Overview for ADA antibody (AA 100-150) (ABIN7449944)
Target
See all ADA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-150
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Purpose
- Rabbit anti-ADA/Adenosine Deaminase Antibody, Affinity Purified
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Predicted Reactivity
- Bovine
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Purification
- Affinity Purified
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Immunogen
- Between AA 100 and 150
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- ADA (Adenosine Deaminase (ADA))
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Alternative Name
- ADA/Adenosine Deaminase
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Background
- Background: The gene ADA encodes the enzyme adenosine deaminase which catalyzes the hydrolysis of adenosine to inosine. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins. Elevated levels of this enzyme have been associated with congenital hemolytic anemia [taken from NCBI Entrez Gene (Gene ID: 100)].
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Gene ID
- 100
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UniProt
- P00813
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
Target
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