ADD2 antibody (AA 1-50)

Catalog No. ABIN7450028

The Rabbit Polyclonal anti-ADD2 antibody has been validated for WB and IP. It is suitable to detect ADD2 in samples from Human.

Quick Overview for ADD2 antibody (AA 1-50) (ABIN7450028)

Target: ADD2 (Adducin 2 (Beta) (ADD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ADD2 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Beta-Adducin Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ADD2

Target: ADD2 (Adducin 2 (Beta) (ADD2))

Alternative Name: Beta-Adducin

Background: Background: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Heterodimers consisting of alpha and gamma subunits have also been described [taken from NCBI Entrez Gene (Gene ID: 119)].

Gene ID: 119

NCBI Accession: NP_001171983

UniProt: P35612

Pathways: Regulation of Actin Filament Polymerization