BLOC1S3 antibody (AA 1-50)

Catalog No. ABIN7450036

This Rabbit Polyclonal antibody specifically detects BLOC1S3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for BLOC1S3 antibody (AA 1-50) (ABIN7450036)

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-BLOC1S3 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-BLOC1S3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BLOC1S3

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Alternative Name: BLOC1S3

Background: Background: BLOC1S3 is a component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. It plays a role in intracellular vesicle trafficking [taken from the Universal Protein Resource (UniProt) Q6QNY0].

Gene ID: 388552

NCBI Accession: NP_997715

UniProt: Q6QNY0