CD247 antibody (AA 114-164)

Catalog No. ABIN7450091

The Rabbit Polyclonal anti-CD247 antibody has been validated for WB and IP. It is suitable to detect CD247 in samples from Human.

Quick Overview for CD247 antibody (AA 114-164) (ABIN7450091)

Target: CD247 (CD247 Molecule (CD247))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD247 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CD247 Antibody

Binding Specificity: AA 114-164

Purpose: Rabbit anti-CD247/CD3Z Antibody, Affinity Purified

Predicted Reactivity: Mouse,Sheep,Pig

Purification: Affinity Purified

Immunogen: Between AA 114 and 164

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD247

Target: CD247 (CD247 Molecule (CD247))

Alternative Name: CD247/CD3Z

Background: Background: T-cell surface glycoprotein CD3 zeta chain is encoded by the gene CD247, also known as CD3Z or CD3 zeta. CD247/CD3 zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response [taken from NCBI Entrez Gene (Gene ID: 919)].

Gene ID: 919

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway