CELSR1 antibody (AA 2775-2825)

Catalog No. ABIN7450102

This Rabbit Polyclonal antibody specifically detects CELSR1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for CELSR1 antibody (AA 2775-2825) (ABIN7450102)

Target: CELSR1 (Cadherin EGF LAG Seven Pass G-Type Receptor 1 (CELSR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELSR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CELSR1 Antibody

Binding Specificity: AA 2775-2825

Purpose: Rabbit anti-CELSR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 2775 and 2825

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CELSR1

Target: CELSR1 (Cadherin EGF LAG Seven Pass G-Type Receptor 1 (CELSR1))

Alternative Name: CELSR1

Background: Background: Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins, a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions.CELSR1 is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis [taken from NCBI Entrez Gene (Gene ID: 9620)].

Gene ID: 9620

NCBI Accession: NP_055061

UniProt: Q9NYQ6

Pathways: Tube Formation, Asymmetric Protein Localization