DOCK2 antibody (AA 1775-1825)

Catalog No. ABIN7450182

This anti-DOCK2 antibody is a Rabbit Polyclonal antibody detecting DOCK2 in WB and IP. Suitable for Human.

Quick Overview for DOCK2 antibody (AA 1775-1825) (ABIN7450182)

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DOCK2 Antibody

Binding Specificity: AA 1775-1825

Purpose: Rabbit anti-DOCK2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1775 and 1825

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Alternative Name: DOCK2

Background: Background: Dedicator of cytokinesis protein 2 (DOCK2) is Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2 [taken from the Universal Protein Resource (UniProt) Q92608].

Gene ID: 1794

UniProt: Q92608