PTPN23 antibody (AA 1586-1636)

Catalog No. ABIN7450316

The Rabbit Polyclonal anti-PTPN23 antibody is suitable to detect PTPN23 in samples from Human. It has been validated for WB and IP.

Quick Overview for PTPN23 antibody (AA 1586-1636) (ABIN7450316)

Target: PTPN23 (Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN23 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PTPN23 Antibody

Binding Specificity: AA 1586-1636

Purpose: Rabbit anti-HD-PTP Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: Between AA 1586 and 1636

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PTPN23

Target: PTPN23 (Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23))

Alternative Name: HD-PTP

Background: Background: His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) Q9H3S7].

Gene ID: 25930

NCBI Accession: NP_056281

UniProt: Q9H3S7