IARS antibody (AA 1212-1262)

Catalog No. ABIN7450348

This Rabbit Polyclonal antibody specifically detects IARS in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for IARS antibody (AA 1212-1262) (ABIN7450348)

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-IARS Antibody

Binding Specificity: AA 1212-1262

Purpose: Rabbit anti-IARS Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1212 and 1262

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IARS

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Alternative Name: IARS

Background: Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase (IARS) belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis [taken from NCBI Entrez Gene (Gene ID: 3376)].

Gene ID: 3376

NCBI Accession: NP_002152

UniProt: P41252