Plexin A3 antibody (AA 1050-1100)

Catalog No. ABIN7450574

The Rabbit Polyclonal anti-Plexin A3 antibody is suitable to detect Plexin A3 in samples from Human. It has been validated for WB and IP.

Quick Overview for Plexin A3 antibody (AA 1050-1100) (ABIN7450574)

Target: Plexin A3 (PLXNA3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Plexin A3 Antibody

Binding Specificity: AA 1050-1100

Purpose: Rabbit anti-Plexin-A3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1050 and 1100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Plexin A3

Target: Plexin A3 (PLXNA3)

Alternative Name: Plexin-A3

Background: Background: Plexin-A3 is a coreceptor for SEMA3A and SEMA3F. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A3 plays a role in axon guidance in the developing nervous system. It regulates the migration of sympathetic neurons, but not of neural crest precursors. Plexin-A3 is required for normal dendrite spine morphology in pyramidal neurons. It may play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm [taken from the Universal Protein Resource (UniProt) P51805].

Gene ID: 55558

NCBI Accession: NP_059984

UniProt: P51805

Pathways: Regulation of Cell Size