RPS24 antibody (AA 83-133)
Quick Overview for RPS24 antibody (AA 83-133) (ABIN7450691)
Target
See all RPS24 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 83-133
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Purpose
- Rabbit anti-RPS24 Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Rat,Golden hamster
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Purification
- Affinity Purified
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Immunogen
- Between AA 83 and 133
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- RPS24 (Ribosomal Protein S24 (RPS24))
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Alternative Name
- RPS24
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Background
- Background: RPS24 (40S ribosomal protein S24) is a component of the 40S ribosomal subunit required for the processesing of pre-rRNA and maturation of the 40S ribosomal subunits. Defects in the RPS24 gene are the cause of Diamond-Blackfan anemia type 3 (DBA3) [MIM:610629]. DBA3 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40 % of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies [taken from the Universal Protein Resource (UniProt) P62847].
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Gene ID
- 6229
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NCBI Accession
- NP_001017
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UniProt
- P62847
Target
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