Snurportin 1 antibody (AA 310-360)

Catalog No. ABIN7450753

This Rabbit Polyclonal antibody specifically detects Snurportin 1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Snurportin 1 antibody (AA 310-360) (ABIN7450753)

Target: Snurportin 1 (SNUPN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Snurportin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Snurportin 1 Antibody

Binding Specificity: AA 310-360

Purpose: Rabbit anti-SNUPN Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 310 and 360

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Snurportin 1

Target: Snurportin 1 (SNUPN)

Alternative Name: SNUPN

Background: Background: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. Snurportin-1 (SNUPN) interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor [taken from NCBI Entrez Gene (Gene ID: 10073)].

Gene ID: 10073

UniProt: O95149

Pathways: Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus