USP48 antibody (AA 985-1035)

Catalog No. ABIN7450886

The Rabbit Polyclonal anti-USP48 antibody has been validated for WB and IP. It is suitable to detect USP48 in samples from Human and Mouse.

Quick Overview for USP48 antibody (AA 985-1035) (ABIN7450886)

Target: USP48 (Ubiquitin Specific Peptidase 48 (USP48))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP48 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-USP48 Antibody

Binding Specificity: AA 985-1035

Purpose: Rabbit anti-USP48 Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken

Purification: Affinity Purified

Immunogen: Between AA 985 and 1035

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for USP48

Target: USP48 (Ubiquitin Specific Peptidase 48 (USP48))

Alternative Name: USP48

Background: Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 48 (USP48) is a member of the C19 peptidase family involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. USP48 is involved in the activation of NF-kappa B via its interaction with RELA and TRAF2.

Gene ID: 84196

NCBI Accession: NP_115612

UniProt: Q86UV5