VAC14 antibody (AA 732-782)

Catalog No. ABIN7450887

This anti-VAC14 antibody is a Rabbit Polyclonal antibody detecting VAC14 in WB and IP. Suitable for Human.

Quick Overview for VAC14 antibody (AA 732-782) (ABIN7450887)

Target: VAC14 (Vac14 Homolog (VAC14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-VAC14 Antibody

Binding Specificity: AA 732-782

Purpose: Rabbit anti-VAC14 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: Between AA 732 and 782

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14

Background: Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].

Gene ID: 55697

UniProt: Q08AM6

Pathways: Inositol Metabolic Process