XRN1 antibody (C-Term)

Catalog No. ABIN7450913

The Rabbit Polyclonal anti-XRN1 antibody has been validated for WB and IP. It is suitable to detect XRN1 in samples from Human and Mouse.

Quick Overview for XRN1 antibody (C-Term) (ABIN7450913)

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-XRN1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-XRN1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1650 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Alternative Name: XRN1

Background: Background: 5'-3' exoribonuclease 1 (XRN1) is a ribonuclease localized in the cytoplasm that functions in mRNA metabolism and is found in messenger ribonucleoprotein (mRNP) complexes. The mouse and yeast homologs of XRN1 are Dhm2 and SEP1 respectively. In a glial cell line, XRN1 is induced by glial cell line-derived growth factor (GDNF) and associates with microtubules. XRN1 has also been identified as a candidate tumor suppressor gene in osteogenic sarcoma.

Gene ID: 54464

UniProt: Q8IZH2, Q6MZS8