VAV3 antibody (AA 200-250)

Catalog No. ABIN7451036

The Rabbit Polyclonal anti-VAV3 antibody has been validated for WB and IP. It is suitable to detect VAV3 in samples from Human.

Quick Overview for VAV3 antibody (AA 200-250) (ABIN7451036)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-VAV3 Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-VAV3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: VAV3

Background: Background: Vav3 is a member of the VAV guanine nucleotide exchange factor (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. Vav3 acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases [taken from NCBI Entrez Gene (Gene ID: 10451)].

Gene ID: 10451

NCBI Accession: NP_006104

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway